Abstract :
Purpose: To evaluate the effect of platelet rich plasma as treatment modality in various etiologies of dry eye.
Materials and Methods: A prospective study was conducted at a tertiary eye care hospital on 65 eyes of 40 patients for a duration of three years, who presented with the complaints of dry eye due to various etiologies. Platelet rich plasma (PRP) was made from the patient’s serum and they were advised to be instilled in topical eyedrop form six times a day.
Results: The study included 29 men and 11 women. The mean age was 40yrs (34.45±15.17), range 10 – 60 years. Dry eye symptoms like burning sensation, itching, dryness, blurred vision and redness were studied and were found to be significantly reduced (p=0.0001)post treatment with PRP after one month. The improvement in symptoms was most likely due to indirect reduction of inflammation. Around 30.7% eyes had improvement in visual acuity of atleast one line. The Schirmer’s test also showed improvement with Schirmer values before treatment being 5.34mm± 2.18 mm to 15.90 mm±7.75mm after treatment. Around 46.87% right eye and 39.9% left eye also had improvement with tear break up time more than 10
sec.
Conclusion: The use of PRP eye drops for the treatment of various etiologies of dry eye was shown to be effective in reducing the symptoms of dry eye without any significant complications.
Keyword :
Corneal erosions, Dry eye, Platelet rich plasma, Tear film Serum.