Abstract :
Introduction: The effect of age on histopathology of the urothelial and non-urothelial bladder tumors has not been studied extensively in literature. This study was undertaken to gain knowledge about this aspect.
Materials and Method: A four year retrospective study, from January 2013 to December 2016 of bladder tumors was carried out in the department of pathology, Sri Ram Murti Smarak institute of medical sciences, Bareilly. The biological material came from TURBT specimens from patients hospitalized for bladder tumors in our institute.
Results: Of all the bladder tumors studied, urothelial tumors comprised 95%. A total of 172 urothelial tumors were detected in age category 40 years and above, as compared to 18 in age category below 40 years. Out of all the urothelial tumors in age category 40 years and above, 65.5% tumors were invasive. In age category 40 years and below, such tumors were 46.6%. All the non-urothelial tumors were detected to be histopathologically invasive and were nine times more common in above 40 year age category than in 40 years and below age category. On studying the non-urothelial variety of bladder tumors we detected that all of them were invasive histopathologically. Besides, these non-urothelial variety of bladder tumors were nine times more common in age group 40 years and above than in age category 40 years and below.
Conclusion: The incidence of bladder tumors of both urothelial and non-urothelial varieties is significantly lower in patients less than 40 years.
Keyword :
Urothelial tumors, Adenocarcinoma, Squamous cell carcinoma, Urinary Bladder, TURBT