Update on atypical meningioma clinicopathological profile


Article PDF :

Veiw Full Text PDF

Article type :

Review Article

Author :

Shashwita S Jagtap, Neha Nanaji Ghadge, Manasi R Bhade, Abhilasha S Jadhav, Pooja Pandey, Sunil Vitthalrao Jagtap

Volume :

10

Issue :

1

Abstract :

Atypical meningioma is a more aggressive form of meningioma and denotes a WHO grade 2 tumor. Case report: A 45-year-old female presented with a sudden onset of persistent generalized headache with dizziness. It was aggressive in nature with associated nausea, vomiting of five days duration. On presentation, the patient was alert, oriented, and cooperative. She did not have any motor or sensory defects. There was no significant any past illness. CT scan of brain showed a large well defined iso to hyperdense lesion in the right lobe of cerebellum, measuring 4 x 3.6 cm. It was causing infiltration of the adjacent brain parenchyma, fourth ventricle, quadrigeminal cistern with effacement. Patient underwent midline suboccipital craniotomy with excision of tumor from the right lobe of cerebellum. On histopathology reported as Atypical meningioma intermediate grade tumor, WHO 2 right cerebellar region. Postoperatively she had no evidence of recurrence on follow-up imaging. Conclusion: Atypical meningioma exhibits characteristic histological features. Patients with an atypical meningioma may shows aggressive nature and requires regular follow up. We present this update with review of atypical meningioma WHO grade 2 tumor for its clinical, radioimaging and histopatholgical findings.

Keyword :

Atypical meningioma, Histopathology, CNS WHO grade 2 tumors