Author :
Ali Mohamed Murad, Ban Hussein Ibraheem, Sarah Ismael Ali, Shatha Sami Hussein*, Liqa Ameer Saad
Volume :
11
Issue :
3
Abstract :
Objectives: To compare the serum pregnancy specific glycoprotein 1 values of women with preeclampsia with the values of healthy pregnant women.
Materials and Methods: A total of 90 pregnant women, whom were recruited during their antenatal care visits to the obstetrical department in Hospital, were included. They were divided into two groups: 45 women with diagnosis of preeclampsia and 45 controls who were the women with healthy pregnancy. Blood samples were collected from both groups and the measurement of pregnancy specific glycoprotein 1 was done using an enzyme immunometric assay.
Results: The groups of preeclampsia pregnant women had markedly lower pregnancy specific glycoprotein 1 than the women with the uneventful pregnancies (9.8±3.8 vs 14.3±6.0 ng/ml; p value
Conclusion: Pregnancies complicated by preeclampsia are associated with decreased maternal serum level of pregnancy specific glycoprotien. This abnormally decreased levels of might be a reflection of stressed or dysfunctional syncytiotrophoblasts, which is related to the pathogenesis of this placental disorder.
Keyword :
Preeclampsia, Pregnancy specific glycoprotein.