Article type :
Case Report
Author :
Swati Smita Sahoo, Deepika Mishra, Meenakshi Mohapatro*, Milan Tripathy, Prasant Kumar Das, Fakir Charan Munda, Shushruta Mohanty, Alkananda Balbantray
Volume :
8
Issue :
3
Abstract :
Introduction: Secretory breast carcinoma (SBC) is one of the rare breast neoplasm with an incidence rate of < 0>
Case Presentation: A 45 -year-old female presented with palpable lump in left breast. FNAC was suggestive of mucinous carcinoma. The diagnosis of SBC was made through histopathology and Immunohistochemistry
Discussion : Recent study report suggested that the disease may also occur at a later age group in contrast to the conventional thought of onset at juvenile age group. Long-term survival is good for these cases. In radiological studies of breast imaging it mimics a benign tumour Immuno-histochemistry and cytogenetic are of the tumour are the ancillary investigations for confirmation of diagnosis.
Conclusion : Although rare diagnosis of SBC can be confirmed by histopathological studies and IHC. It is slowly progressive but has a good prognosis.
Keyword :
Secretory breast cancer (SBC), Immunohistochemistry, Balanced translocation t (12, 15), ETV6-NTRK3 Gene fusion.