Saliva: A double-edged sword


Article PDF :

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Article type :

Review Article

Author :

Rishitha Sajja, Rishitha Sajja

Volume :

11

Issue :

3

Abstract :

The COVID-19 virus is primarily known to affect the respiratory system of infected individuals. The mode of transmission is predominantly said to be through droplet spread, and this poses a great threat to the dental profession, as most dental treatments are aerosol-generating procedures (AGPs). The virulence of the COVID-19 virus initiates an antiviral response after the viral genome is released into the human cell cytoplasm. ACE2 receptors are predominantly seen in the salivary gland and tongue tissues. The saliva collected directly from the salivary glands had shown nucleic acid of the COVID-19 virus. Most dental treatments involve exposure to saliva aerosols, blood, and sharp instruments. Hence, it is important to understand the role of saliva in the transmission of COVID-19 virus. This review highlights the physiobiological aspects of Saliva, diagnostic tests available, and recommendations for dentists to facilitate dental treatment with a low risk of disease transmission.

Keyword :

Saliva, COVID-19, Infection; Infection control, Nasopharyngeal swab; Oropharyngeal swab.