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Role of MRI diffusion tensor imaging in the assessment of neurological diagnosis


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Article type :

Review Article

Author :

Ankit Kumar , Viswanath Pratap Singh, Pushpendra Kumar Rajput, Shiv kailash Yadav, MS Shmriti*

Volume :

11

Issue :

1

Abstract :

MRI Diffusion Tensor Imaging (DTI) has emerged as a pivotal tool in the assessment of neurological disorders, providing detailed insights into the microstructural integrity of brain tissue. By measuring the diffusion of water molecules, DTI enables visualization and mapping of white matter tracts, essential for understanding connectivity disruptions in conditions such as multiple sclerosis, stroke, and traumatic brain injury. Quantitative metrics derived from DTI, including fractional anisotropy (FA) and diffusivity indices (MD, AD, RD), serve as biomarkers for axonal integrity, myelination, and gliosis. DTI's ability to differentiate between various pathologies aids in diagnosis and guides therapeutic strategies. Moreover, its role extends to monitoring disease progression, assessing treatment efficacy, and facilitating surgical planning by identifying critical neural pathways. MRI Diffusion Tensor Imaging (DTI) has revolutionized the assessment of neurological disorders by offering unparalleled insights into the microstructural integrity of brain tissue. This advanced imaging technique measures the diffusion of water molecules in neural pathways, allowing for precise visualization and mapping of white matter tracts. These metrics not only aid in the accurate diagnosis and differential diagnosis of conditions such as dementia, epilepsy, and traumatic brain injury but also facilitate monitoring of disease progression and assessment of treatment response. Furthermore, DTI plays a crucial role in pre-surgical planning by identifying critical neural structures, thereby minimizing surgical risks and optimizing patient outcomes. This abstract underscores DTI's pivotal role in advancing neuroimaging capabilities, significantly enhancing clinical management and research endeavors in neurological medicine.

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