Abstract :
Context: Despite of prophylaxis, nausea or vomiting is most common in the postoperative period, may leads to unanticipated readmission, prolonged hospital stay and patient’s frustration. Earlier studies have reported conflicting results of dextrose on postoperative nausea and vomiting hence we designed this study.
Aim: Testing the role of intravenous 5% dextrose on reducing the frequency of postoperative nausea and vomiting.
Study design: A prospective, randomized, double-blind, placebo-controlled study.
Methods: In this study, we allocated 90 healthy patients scheduled for tympanoplasty under general anesthesia. The participants were randomized into two groups (n=45) to receive either Ringer’s lactate solution (group C) or 5% dextrose in Ringer’s lactate solution (group D) intravenously following surgery. A standard technique was applied for general anesthesia in all patients and single dose of ondansetron 4 mg was given intravenously half-hour before recovery from anesthesia. Postoperative nausea and vomiting scores, antiemetic doses were recorded at 0, 30, 60, 90, 120 min and 24 hours. The duration of stay in post-anesthesia care unit was also noted. The data recorded were analyzed using student t-test and chi-square test. A value of P 0.05). Conversely, patients in group D consumed less antiemetic doses (P = 0.004), and had a short duration of stay in the post-anesthesia care unit (P
Keyword :
Dextrose, Nausea, Postoperative, Prevention, Vomiting