Abstract :
Malaria, caused by Plasmodium species, remains a major global health concern, particularly in tropical and subtropical regions. Despite the significant progress in malaria treatment, drug resistance has rendered many current therapies ineffective. As a result, the search for novel antimalarial compounds is crucial. Heterocyclic compounds, due to their structural diversity and bioactivity, have emerged as promising candidates for the development of new antimalarial agents. This review highlights the role of various heterocyclic compounds, including their chemical structures, mechanisms of action, and potential therapeutic applications in the treatment of malaria.
Keyword :
Quinoline, Isoquinoline alkaloids, Imidazol, Pyrazolopyrimidine derivatives, Pyrazole derivatives.