Abstract :
Herpes labialis remains exceptionally prevailing and is one of the most common human viral infections across the globe. Recurrent herpes labialis usually starts from the preliminary viral infection by herpes simplex virus type 1 (HSV-1) which consequently exhibits with or without symptoms. Reactivation of this virus is started by psychosocial reasons such as anxiety, febrile surroundings, ultraviolet light vulnerability, or specific dietary insufficiency. This virus infection is also categorized by continuous transitions between chronic-latent and acute-recurrent phases, permitting the virus to opportunistically avoid immunity and permit the spread to other susceptible hosts concurrently. According to WHO, an approximate 3.7 billion people under age 50 (67%) have HSV-1 infection globally. In the United States of America (USA), HSV-1 affects 57% to 80% of adults, while in Asia, the numbers are essentially high for adults (75%) especially those from low socioeconomic standings, and children (50%) due to epidemiological shifts, showing decreased seroprevalence in the young cohorts. It has been reported that recurrent herpes labialis (RHL) affects about one-third of the population in the USA and presents as inflamed/painful oral lesions with conditional distress. Some patients usually encounter up to six episodes per year which can be troublesome for patients and their families.
Keyword :
Herpes labialis, WHO, Seroprevalence, Oral Lesions, Herpes Simplex Virus