Abstract :
Introduction: Malignant Primary osteosarcomas of the breast are rare mammary sarcomas with aggressive
potential. Unlike skeletal osteosarcomas which occurs in young adults, these tumors predominantly occur
in the older age group. It is essential to clearly distinguish primary osteosarcomas of the breast from the
common breast carcinomas since the treatment model for the former follows a multidisciplinary approach
as for sarcomas affecting other anatomical locations.
Case History: A seventy year old female presented with swelling in the right breast since three years
with progressive increase in size and mammographic evidence showing a well circumscribed dense lesion
with focal calcification favouring fibroadenoma. While cytosmears showed atypical cells obscured by
haemorrhage, trucut biopsy showed malignant features with a possible differential of Phyllodes tumour and
metaplastic carcinoma with osseous elements. Subsequent mastectomy was done and histology revealed
a primary osteosarcoma of the breast. Primary osteosarcoma of breast is an extra -osseous manifestation
which is diagnosed after excluding the possibility of primary from the underlying bones of sternum and rib,
malignant phyllodes and metaplastic carcinoma. Considering the rarity of this entity we believe that each
case can contribute to the improvement in the diagnosis and management of this disease.
Keyword :
Breast malignancy, Primary osteosarcoma of breast, Mastectomy, Histopathology.