Abstract :
Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder which is characterized by diffuse palmoplantar keratoderma and precocious aggressive periodontitis, resulting in premature loss of deciduous and permanent dentition at a very early age. Several etiopathogenic factors are responsible for the syndrome, like immunologic alterations, genetic mutations, and also the role of microorganisms. Dentists play a major role in the diagnosis and management of PLS as there are characteristic manifestations like periodontal destruction at an early age and an early eruption of permanent teeth. Here, we are presenting an elaborate review of PLS, its etiopathogenesis, clinical presentation, and management options.
Keyword :
Periodontitis, Modified Complete Dentures, Primary and Permanent dentition, Palmoplantar Keratoderma.