Oral leukoplakia: risk of malignant transformation and the importance of surgical excision


Article PDF :

Veiw Full Text PDF

Article type :

Original Article

Author :

Mariem Meddeb, Abdellatif Chokri, Faten Hammedi, Karim Masmoudi, Hajer Hentati, Jamil Selmi

Volume :

4

Issue :

3

Abstract :

Leukoplakia is the most frequent potentially malignant lesion of the oral mucosa. Its diagnostic and therapeutic present a challenge for dentist. Two clinical cases of oral leukoplakia were reported. The first was a patient using chewed tobacco consulted for a verrucous oral lesion that was surgically completely removed. Histopathological examination of the specimen revealed verrucous carcinoma. The second was a smoker man presenting an oral leukoplakia with fungal infection. After antimycotic treatment and periodic follow up, the clinical signs of candidiasis regressed but the mucosal white patch persisted. A large part of the lesion was removed. Histopathological examination indicated a well-differentiated squamous cell carcinoma.

Keyword :

Leukoplakia, Oral mucosa, Biopsy, Dysplasia, Carcinoma