Abstract :
Introduction: In addition to anticonvulsant property of gabapentin, it was demonstrated that gabapentin also possesses analgesic property. In this randomized control trial the efficacy of gabapentin for postoperative pain relief was studied on 60 adult patients of either sex, belonging to ASA grade I or II, in the age range of 18-60 years posted for lower limb surgeries under spinal analgesia.
Methods: The patients were randomly divided into two groups of 30 patients each. Group A patients (n=30) received oral gabapentin 1200 mg 2 hours prior to scheduled surgery and the same dose was given at 9:00 am on the first and second postoperative days. Group B (n=30) served as control group received only placebo capsules. Subarachnoid block was established in both the groups by administering 4 ml of hyperbaric bupivacaine. Vital parameters such as heart rate, blood pressure respiratory rate along with pain assessment (VAS) were recorded at regular intervals in the postoperative period. Rescue analgesia was provided with intramuscular butorphanol.
Results: It was observed that patients in group A exhibited excellent quality of postoperative pain relief as compared to group B (P
Keyword :
Gabapentin, Butorphanol, Postoperative pain, Multimodal analgesia, Lower limb surgeries, Spinal analgesia