Mycological profile of keratomycosis in a tertiary care centre from Pune Maharashtra


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Article type :

Original Article

Author :

Purabi Baral, Smita K. Deshpande, Renu R. Bharadwaj

Volume :

4

Issue :

2

Abstract :

Introduction: Microbial keratitis remains a leading cause of corneal ulcer and blindness worldwide. Mycotic keratitis has emerged as a major ophthalmic problem and contributes to 6-53% of all corneal infections worldwide. Thus the present study was undertaken to assess the spectrum of fungal causes of keratitis in BJGMC & SGH, Pune. Aims and Objectives: 1. To establish the microbiological profile of keratitis. 2. To determine the mycological profile of keratitis. Materials and Methods: The present prospective study was conducted over a period of twelve months in a tertiary care hospital. The study was undertaken to evaluate the etiological profile of keratomycosis with a special reference to mycotic etiology. The corneal scrapings were collected aseptically and processed by direct microscopic methods and standard culture techniques. Results: Of 90 cases of keratitis screened, culture yielded growth in 50 cases (55.6%). These were included in the study. Out of these 50 cases of growth, fungi were isolated in 32% and bacteria in 64% cases. Mixed growth of bacteria and fungi was found in4% cases. Most common fungus found were Fusarium spp. (44.4%) followed by Aspergillus spp. (27.8%), Alternaria spp. (11.1%), Curvulariaspp (11.1%) and Acremonium spp (5.6%). Conclusion: Routine surveillance of fungal keratitis is necessary to know the existing and emerging pattern of pathogens and to prevent inappropriate use of antimicrobial therapy.

Keyword :

Keratitis, Fungus, Aspergellus, Keratomycosis.