Abstract :
Renal cell carcinoma has been classified into various subtypes with newer emerging entities. The tumors have different cytogenetic, molecular characteristics and recognizing histologic patterns of Renal cell carcinoma(RCC) is important not only for correct diagnosis, but also for providing insight into the biological behavior of the tumor and subsequent appropriate medical care for the patient. Pigments other than hemosiderin have been described in renal cell carcinoma but a very few case reports are there of melanin deposition. Melanotic tumors, either primary or metastatic, are rare in the kidney. Herein we present a rare case of RCC with melanocytic differentiation, a variant that may lead to diagnostic error and may warrant the classification of this entity separately.
Keyword :
Renal cell carcinoma, Melanin, Immunohistochemistry and HMB45