Abstract :
It is a key element in the metabolism of almost all living organisms. In humans, iron is an essential component of hundreds of proteins and enzymes. Ferritin is a protein in the body that binds to iron. It is found in the liver, spleen, skeletal muscles, and bone marrow. Only a small amount of ferritin is found in the blood. The amount of ferritin in the blood shows how much iron is stored in the body. Iron moves through the blood attached to a protein called transferrin. Total iron binding capacity (Total Iron Binding Capacity) is the test to assess the iron carrying capacity of transferrin.
Objective: The role of serum iron in Oral Submucous Fibrosis is well established by many researchers. This study probes into the role of serum iron, ferritin as well as TIBC in the pathogenesis and treatment planning of OSMF and Leukoplakia.
Materials and Method: The study group comprised of total 50 subjects. 25 cases with OSMF and leukoplakia were & 25 patients with the normal mucosa but with deleterious habits were taken as controls.
Results: The iron, ferritin and total iron binding capacity showed altered values in OSMF & Leukoplakia and also the iron indices were altered with the habit index.
Keyword :
Chewers, Ferritin, Iron, Leukoplakia, Oral Submucous Fibrosis, Transferrin