Abstract :
Indole is a valuable compound which has becomeprominent in medicinal chemistry because of its variousbiological
activities. Indole ring is present in various marineor terrestrial natural compounds, which have useful
biologicalproperties. In last few years it was reported that indole, itsbioisosters and derivatives had antimicrobial
activity againstgramnegative, grampositive bacteria and yeast candidaalbicans antimicrobial activity. A large
number of efforts were made to synthesizedifferent heterocyclic compounds and their derivatives in thepast decode
and were found to possess promising antitumor, anticonvulsant, antimicrobial anti tubercular and anti diabetic
activities. Although indole moiety is very small but isfascinated by scientists because of the diverse
biologicalactivities by not only indole but its various substitutedderivatives as well. This revisers is focused on the
indole andits derivatives that are now in development. This review brings about an overview of novel drug
molecules of indole and also urges to synthesize moremoieties for better enhanced biological activity.
Keywords: Indole, Antimalarial, Anticancer, Antimicrobial, Antihypertensive
Keyword :
Indole, Antimalarial, Anticancer, Antimicrobial, Antihypertensive