Incidental papillary carcinoma originating from a thyroglossal duct cyst: Diagnosis by histopathology & immunohistochemistry


Article PDF :

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Article type :

Case Report

Author :

Jalli Pravallika, Garima Bhanagar, Sanjay Kumar*, G. Mahantesh, Abhinav Taneja, Naveet Kumar Singh

Volume :

12

Issue :

1

Abstract :

Papillary thyroid carcinoma (PTC) arising from a thyroglossal duct cyst (TDC) is a rare, incidental diagnosis, occurring in less than 1% of TDC cases. These cysts typically present as asymptomatic midline neck swellings and are often not associated with any significant clinical symptoms or changes in laboratory parameters. A 28-year-old woman presented to the ENT outpatient department with a 13-year history of a slow-growing swelling on the left side of her chin and neck. The swelling was not accompanied by symptoms such as difficulty swallowing (dysphagia), difficulty breathing (dyspnea), or changes in voice. Comprehensive clinical evaluation, imaging studies, and laboratory analyses were conducted to assess and manage the case of PTC arising within the TDC. Current evidence suggests that performing a routine thyroidectomy may not significantly alter the prognosis of papillary carcinoma within a TDC, underscoring the need for a tailored approach based on individual patient assessments and risk factors.

Keyword :

Thyroglossal duct cyst, Papillary thyroid carcinoma.