Author :
Faiyaz Ahmad, Ankita Mittal, Deepti Arora, Seema Awasthi, Shyamoli Dutta, Ashutosh Kumar
Volume :
6
Issue :
4
Abstract :
Introduction: Cutaneous granulomatous lesions are very common encountered by pathologist and
dermatologists. Granulomatous dermatoses can be seen in infectious as well as non-infectious conditions
leading to chronic inflammation. Clinical features are overlapping, a confirmatory causative finding is
essential for the management of patient as treatment varies greatly according to cause. Histopathology
remains a gold standard for diagnosis as well as further subtyping of granulomatous inflammatory disorders
of skin.
Materials and Methods: A retrospective study of skin lesion biopsies performed for 2 years and 2 months,
from November 2016 to January 2019. Clinical details were obtained from requisition forms and the cases
of granulomatous lesions were diagnosed and subclassified with the help of H&E and special stains.
Result: The study includes 70 cases. A predominance of male were found with M:F ratio of 1.3:1.
21 to 30 years of age group was the commonest for granulomatous lesions with 34.3% of cases. Infectious
granulomatous dermatoses were far high than non-infectious ones. Leprosy remained the major etiology
followed by tuberculosis of skin.
Conclusion: Leprosy contribute the major cause of granulomatous dermatoses in this study.
Histopathology is gold standard for diagnosis and subclassification of cutaneous granulomatous lesion
with a proper history and clinical details.
Keyword :
Granuloma, Leprosy, Skin biopsy.