Abstract :
In this work we synthesized a novel series of N’-substituted-Nâ€-[4-hydroxy-3-(1H-indol-2-yl)
phenyldicarbonodithioimidediamide by green synthesis parameters from N’-[4-hydroxy-3-(1H-indol-2-yl) phenyl]
thiourea and substituted thioformamide. Previously such types of reactions were carried out in acetone medium but
we developed new reaction condition in which percentage of acetone was reduced. During synthesis we carried out
these reactions in various compositions of ethanol-acetone medium. This method has broad applications due to its
efficiency for accelerating a course of organic reactions and increases yields, higher selectivity and lower quantities
of byproducts. This method has consequently easier work-up and products obtained are in comparatively pure form.
In 70% ethanol-acetone medium we got maximum yields. Justification and confirmations of structure of synthesized
compounds were carried by usual elemental analysis, chemical characteristics and spectral studies.
Keywords: N’-Substituted-Nâ€-[4-hydroxy-3-(1H-indol-2-yl) phenyldicarbonodithioimide diamide, thioformamide
Keyword :
N’-Substituted-Nâ€-[4-hydroxy-3-(1H-indol-2-yl) phenyldicarbonodithioimide diamide, thioformamide