Abstract :
Hypothyroidism is a syndrome resulting from thyroid hormone deficiency
or rarely inefficacy. It is a common endocrinological problem affecting
especially women and the elderly. Thyroid hormones play an important
role in synthesis, metabolism and mobilization of lipids. One of the most
important symptoms of hypothyroidism is weight gain or inability to lose
weight. The rapid increase in the prevalence of obesity in the past 20 to 30
years emphasizes the important role of lifestyle and environmental factors,
because genetic changes could not have occurred so rapidly.Obesity is a
complicated process that depends on signals of satiety and hunger,
genetics, endocrine abnormalities, and other factors. Our study purposes
to investigate the relationship between BMI and thyroid function in patients of subclinical hypothyroidism.
Objective of this study is to correlate thyroid stimulating hormones (TSH) and body mass index (BMI) in male and
female patients with subclinical hypothyroidism.
This cross sectional study included 42 Subclinical hypothyroid patients, both males and females between 20-45 years
of age and without a history of alcohol or tobacco consumption, history of any cardiovascular disorders or diabetes
mellitus and any drug history like corticosteroids, beta blockers. and TSH test estimated by VITROS 5600 integrated
analyzer and correlated with body mass index.
The results showed a positive Correlation analysis in subclinical Hypothyroid males between BMI and TSH, (r= 0.47),
which was found to be statistically significant (p=0.02*) in case of subclinical Hypothyroid females the results indicated
positive correlation between BMI and TSH (r= 0.58) which was found to be statistically significant (p=0.005*).
A strong positive correlation between Body Mass Index (BMI) and Thyroid stimulating hormones (TSH).
Keyword :
TSH (Thyroid Stimulating Hormone), BMI (Body Mass Index), SCH (Subclinical hypothyroid), SD (Standard Deviation), WHO (World Health Organization).