Comparison of the effects of pre loading with 6% hydroxy-ethyl starch 130/0.4 versus Ringer lactate in preventing spinal anaesthesia induced hypotension in Caesarean section


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Article type :

Original Article

Author :

Vijay Narayanan S, Mohamed Mubarack A, Iniya R, Rajalekshmi M

Volume :

3

Issue :

3

Abstract :

Background: Hypotension after spinal anaesthesia is preventable by adequate pre-loading with colloids or crystalloids. Women posted for emergency caesarean section are more vulnerable for hypotension as they are not preloaded adequately due to time constraints. The idea of the study is to maintain haemodynamics by administering preload solution without any delay. Here 6% Hydoxyethyl starch (HES) is compared with Ringer lactate (RL) as a preloading solution. Materials and Methods: 50 pregnant women posted for emergency caesarean section were randomly allocated into 2 groups – Group H of 25 women received 500 ml of 6% HES and Group R of 25 women received 500 ml of RL intravenously as preload prior to spinal anaesthesia. The requirement of ephedrine to counter hypotension and the changes in the haemodynamic parameters were noted. Statistical analysis was done using Student’s ‘t’ test, Fisher’s test and Chi square test, and p

Keyword :

6% Hydroxyethyl starch, Hypotension, Pre-loading, Spinal anaesthesia, Emergency caesarean section