Abstract :
Background: Patients undergoing general anaesthesia are exposed to both intravenous and inhalational agents, which can induce various physiological changes. The use of a single agent for anaesthesia, however, has been shown to potentially reduce these changes. This study aimed with the primary objective to compare the recovery profiles of patients undergoing fibroadenoma excision surgery under sevoflurane or target-controlled infusion propofol, as assessed by the Clinical Recovery Score. The secondary objectives was evaluating the ease of Laryngeal Mask Airway (LMA) insertion, monitoring side effects, and assessing the recovery profile using the Post-Anaesthesia Discharge Scoring (PADSS) Score.
Materials and Methods: This prospective randomised study included 90 female patients presenting with fibroadenoma, who were allocated into three groups via computerized randomization. Group P received Inj. Propofol 1% titrated in TCI. Group S received Sevoflurane, titrated to maintain an end-tidal concentration of 2%. Group C received general anaesthesia, where patients were induced with Inj. Propofol at 2 mg/kg, and anaesthetic depth was maintained with Sevoflurane. Depth of anaesthesia was monitored using the Bispectral Index (BIS). Post-procedure, the recovery profile of patients was assessed using the Clinical Recovery Score (CRS) and the Post-Anaesthesia Discharge Scoring (PADSS) scores.
Results: Patients in Group P (Propofol) demonstrated a significantly better recovery, with a Clinical Recovery Score (CRS) of 11.8 ± 0.41 (p-value < 0>
Conclusion: Total intravenous anaesthesia with propofol led to superior recovery outcomes, facilitating earlier discharge compared to sevoflurane or a combination of both agents.
Keyword :
Propofol, Sevoflurane, Anaesthesia, Fibroadenoma.