Comparison of Ketamine versus Fentanyl as an adjuvant with Propofol for inserting Laryngeal Mask Airway


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Article type :

Original Article

Author :

Mohan Kumar RM, Muralidhara Danappa Patel, Hemavathi Balachander, Satyen Parida

Volume :

4

Issue :

2

Abstract :

Materials and Methods: 120 adult, ASA 1 and 2 patients were randomly allocated into two groups, propofol-ketamine (PK) and propofol-fentanyl (PF), (n=60 in each group) Baseline parameters- oxygen saturation (SpO2), Mean Blood Pressure (BP), Pulse Rate (PR) and End Tidal carbon dioxide (EtCO2), were recorded following which 1µg/ kg Fentanyl to the PF group & 0.5 mg/kg Ketamine to the PK group was given intravenously. Induction was initiated with infusion of 1% Propofol @ 1mg/ kg/ min with a syringe pump to avoid apnea. Tolerance to jaw thrust was regarded as end point for LMA insertion. Statistical analysis done by Parametric and non parametric values were analyzed using student’s unpaired t-test and Mann Whitney’s U test respectively. Intragroup differences analyzed by one-way ANOVA with significance using Tukey’s method. The incidence of apnea was analyzed using Chi- square test. P

Keyword :

Propofol, Ketamine, Fentanyl, Laryngeal mask airway, General anaesthesia