Abstract :
Background: Diabetes mellitus causes several ophthalmic complications including retinopathy, cataract, and damage to the anterior chamber of the eye including various layers of the cornea.
Aim: To compare endothelial cell loss after phacoemulsification surgery for cataracts among diabetics and non-diabetic patients.
Materials and Methods: A single-centre, hospital-based, prospective, comparative, 1:1 observational study enrolling participants a total of 200 participants were enrolled (100 diabetic and non-diabetic) and were followed up from the preoperative period to 3 months after surgery. The data pertaining to endothelial cell density, coefficient of variance, endothelial cell hexagonality and central corneal thickness were recorded using specular microscopy before, 1-, 7-, 30-, and 90 days after cataract surgery.
Results: There was a significant difference (p10 years of diabetes and highest among patients with < 5> 10 years of diabetes was 65.7%, 62.5% and 57.5%, respectively.
Conclusion: In comparison to non-diabetic patients, there was a considerable loss of endothelial cell function among diabetic individuals following cataract surgery. Furthermore, a slower and poorer healing response was seen in patients with diabetes.
Keyword :
Endothelial cell, Phacoemulsification, Endothelial cell hexagonality, Central corneal.