Abstract :
Introduction and Objectives: Caesarean sections generally done under subarachnoid block using 0.5%
hyperbaric bupivacaine as the local anaesthetic of choice. As most caesarean sections are of short duration,
we decided to study whether 1% 2-chloroprocaine would be suitable alternative to bupivacaine with primary
outcome being duration of sensory blockade in elective lower segment caesarean sections.
Materials and Methods: In this prospective study, 60 pregnant females belonging to ASA status 1 and
2, posted for elective lower segment caesarean section were equally randomized into two groups. The first
group received 1% chloroprocaine 25 mg (2.5 ml, Group CP) and second group received 0.5% hyperbaric
bupivacaine 10 mg (2.0 ml, Group B), intrathecally. We measured the level of sensory and motor blockade,
duration of sensory blockade and side effects.
Results: Mean duration of sensory blockade was 61.83 23.54 minutes for group CP, which is
significantly shorter than group B which had 174.67 41.17 minutes (p Value clinically significant incidences of hypotension (53.33% Vs 30%) compared to group CP.
Conclusion: Intrathecal low dose 1 % chloroprocaine is a safe and suitable alternative to low dose 0.5%
hyperbaric bupivacaine for an uncomplicated elective lower segment caesarean section.
Keyword :
1% 2-Chloroprocaine 0.5% Hyperbaric bupivacaine, Subarachnoid block, Lower segment caesarean section.