Abstract :
Helicobacter pylori earlier known as Campylobacter pylori is a gram negative bacterias that colonizes the
gastric epithelium of Humans.
Helicobacter pylori is considered as the most successful pathogen as more than 50% population have
Helicobacter pylori in their upper Gastrointestinal tract.
It is usually observed that 80% of the infected population is asymptomatic to the bacterium. The infection of
Helicobacter pylori is more common in developing countries like India than developed western countries.
Helicobacter pylori is a major cause of gastro-duodenal injury and is also related to gastric cancer, thus
detection of the bacterium is must for proper treatment.
This paper is a comparative evaluation of traditional stains used for the diagnosis of H. pylori. Main focus
is laid on special stains such as Giemsa stain, toluidine blue and modified H&E staining method.
The most common way of detecting Helicobacter pylori is by histopathological examination in which
biopsies from stomach region (Body, fundus and antrum) are examined.
Keyword :
Helicobacter pylori diagnosis histopathology, GI Biopsies tissue staining.