Author :
Nanda Patil , Sujata Kanetkar , Nidhi Goswami* , Neha Desai
Volume :
10
Issue :
1
Abstract :
Introduction: Outcome of patients with urothelial carcinoma is largely dependent on histopathological type & grade of tumor. WHO has proposed classification for diagnosing & grading papillary urothelial neoplasms in an attempt to more precisely predict progression of disease. Present study was undertaken to diagnose & classify urothelial neoplasms based on WHO classification 2022.
Results: The study included histopathological evaluation of urothelial neoplasm of bladder and was carried out in the department of pathology for 3 years from 2018 - 2020 which included 30 cases. Commonest age group was 61 - 70 years with a mean age of 62 years. Male preponderance was observed. Commonest clinical presentation was frequency of micturition 29 cases (96.6%) followed by hematuria in 18 cases (60%) and painful micturition in 16 cases (53.3%).
Histopathological diagnosis included low grade urothelial carcinoma 17 cases (56.6%), high grade urothelial carcinoma 7 cases (23.3%), muscle invasive urothelial carcinoma of high grade 3 cases (10.0%), PUNLMP 2 cases (6.6%) & squamous cell carcinoma with invasion in 1 case (3.3%). Divergent differentiation was seen in 2 cases in the form of squamous cell carcinoma (6.6%).
Conclusion: Clinicopathological profiling along with histopathological grading is very important for determining the prognosis in urothelial carcinoma of bladder.
Keyword :
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