Abstract :
Aim and Objectives: To study the clinical profile and outcome of thrombocytopenia in pregnancy.To study the etiologies of thrombocytopenia in pregnancy. To study the maternal and perinatal outcome in thrombocytopenia in pregnancy.
Materials and Methods: This is an observational retrospective study in which 200 pregnant women who had thrombocytopenia were recruited from department of obstetrics and gynecology at Gandhi hospital.
Results: The present study gives information about the etiology of thrombocytopenia in pregnancy and fetomaternal outcome. Out of 200 cases, 88 cases belongs to pregnancy induced hypertension which is considered as the most common etiology followed by gestational thrombocytopenia. Incidence of abruption was significantly high mainly in pregnancy induced hypertensive cases. The maternal and perinatal complications were lower in gestational thrombocytopenia compared with other etiologies. High rates of preterm deliveries were observed among women with hypertensive disorders. Adverse perinatal outcome was mostly associated with hypertensive disorders especially HELLP syndrome.
Conclusion: The common cause of thrombocytopenia in pregnancy in this study is mainly hypertensive disorders. Patients with gestational thrombocytopenia have favorable maternal and perinatal outcome. On the other hand, preeclampsia and HELLP syndrome are associated with adverse perinatal outcome like IUGR and intrauterine fetal death.
Keyword :
Thrombocytopenia, Pregnancy, Preeclampsia, Intrauterine growth restriction.