Abstract :
Introduction: Gingivitis and periodontitis are linked to the excessive production of oxygen species and some free radicals), which can contribute to tissue destruction. Coenzyme Q10 (CoQ10), a powerful natural antioxidant, exists in two forms: the oxidized form and the reduced form. It functions as a ROS scavenger and may help reduce periodontal inflammation.Aim: To assess and compare the therapeutic efficacy of topical Coenzyme Q10 application versus conventional scaling and root planing alone in enhancing periodontal health, as measured by changes in the Gingival Index and the Community Periodontal Index of Treatment Needs (CPITN) at baseline, 3 weeks, and 6 weeks.Materials and Methods: A total of 32 diabetic patients divided into 2 groups. One group is exposed to topical application (extrasulcular) Coenzyme Q10 & SRP and 2nd group is exposed to SRP only. Clinical parameters, including the Gingival Index and CPITN index, were evaluated at baseline, at the end of the 3rd week, and at the 6th week.Results: Intra-group comparison was done both the indices gingival index (GI), Community periodontal index of treatment needs(CPITN) showed significant reduction in the scores but the results where statistically non-significant in all 2 treatment groups.Conclusion: Antioxidant is effective in reducing the gingival inflammation among diabetic patients.
Keyword :
Antioxidants, Periodontitis, Coenzyme Q10, Gingivitis, Topical application