Abstract :
Background: Central macular thickness (CMT) may undergo significant changes after cataract surgery, particularly in diabetic individuals. The temperature of balanced salt solution (BSS) used during phacoemulsification may influence postoperative inflammatory response and macular changes.Aim and Objective: To assess and compare the central macular thickness (CMT) in diabetic and non-diabetic patients undergoing phacoemulsification using normothermic and hypothermic BSS.Materials and Methods: The study consisted of 140 participants divided equally into four groups of 35 each. Group 1 – NDMR: Nondiabetics who received room temperature BSS; Group 2 – NDMC: Nondiabetics who received cold BSS; Group 3 – DMR: Diabetics who received room temperature BSS; and Group 4 – DMC: Diabetics who received cold BSS. The cold BSS used was at a temperature of 4oC and room temperature BSS used was normothermic and was in the range between 34 – 36oC. CMT was measured pre and post-operatively using a spectral domain optical coherence tomography scan and compared.Results: The CMT values were significantly different between the NDMR (non-diabetic patients receiving room temperature BSS) and NDMC (non-diabetic patients receiving cold [4oC] BSS) consistently at POD 7, 28 and 42, with CMT being higher in those who were given room temperature BSS.Conclusion: The incidence of cystoid macular edema is less in non-diabetics than diabetics who were subjected to hypothermic BSS.
Keyword :
Balanced salt solution, Cold vs room temp irrigating solution, Diabetics, Central macular thickness, Phacoemulsification, Cystoid macular edema.