Abstract :
Objective: to determine the relationship between pre-operative C1 protein (CRP) and post-elective cardiac surgery
complications, including atrial fibrillation, systemic inflammatory response syndrome, wound infection, acute renal
failure, shock, and death.
Materials and Methods: This prospective observational study was conducted at the Department of Cardiology Mayo
Hospital, Lahore for the period of 1 year from December 2016 to December 2017. Patients who underwent
cardiovascular surgery at CRP levels were measured in all patients in the morning following surgery. Patients were
categorized as Group A (CRP 2 mg / dL) and hospitalization was followed by
postoperative complications.
Results: 140 patients (100 (70%) male and 40 (30% female) were studied; There were 97 (65.1%) patients with PCR
2 mg / dl (Group B). The average age in group A was 43.6 ± 13.2
years and in group B was 48.9 ± 13.4 years. The overall mortality rate in our study was 3.35% (n = 5). Systemic
inflammatory response syndrome (SIRS) was 81 (54.4%); B group was 34 (65.4%) and 47 (48.5%) group (p =
0.048). Acute renal failure developed in 26 (50%) patients in group B and 28 (28.9%) in patients (p = 0.011).
wound infections were observed in 13 (25%) patients and 11 (11.3%) in the high PCR from the low CRP group (p =
0.031). There was no significant statistically difference in atrial fibrillation and shock in both groups. Death rate
was same in both groups. Conclusion: Preoperative high CRP levels may be postoperative complications such as
SIRS, acute renal failure after elective cardiac surgery and wound infection.
Keywords: C Reactive Proteins, Cardiovascular Surgery, Postoperative Complications.
Keyword :
C Reactive Proteins, Cardiovascular Surgery, Postoperative Complications.