Assessment on the evaluation of corneal endothelial cell morphology and cell count in cataract with pseudoexfoliation


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Article type :

Original Article

Author :

Akshatha Javagal*, Sandeep K, Kavitha Chikkanayakanahalli, Pavana Acharya, Sreelekshmi S R, Narendra N

Volume :

9

Issue :

1

Abstract :

Purpose: To assess the cell morphology & evaluate corneal endothelial cell count in patients suffering from cataract with pseudoexfoliation (PEX). Materials and Methods: A cross-sectional study was planned and conducted in 40 eyes of patients, corneal endothelial cell density (CD), central corneal thickness (CCT) and coefficient of variation (CV) & percentage of hexagonal cells (6A) in cell size were assessed with application of specular microscope Results: The mean age of patients with cataract & PEX was 68.5 years. 58% were males. Lower CD was found in 40% patients of 50-59 years & 60% patients 60-69 years. Patients above 70 years had normal CD for age. 6A was low in 90% of PEX corneas. Abnormal CV was seen in 67.5% patients. CCT, CD & 6A were lower in PEX glaucoma compared to PEX. Conclusion: Our study confirms the existence of quantitative and qualitative abnormalities in corneal endothelial cells with PEX especially when IOP is high.

Keyword :

Pseudoexfoliation, Cataract.