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Article type :

Original Article

Author :

R A Analike, A C Ihim, S C Iweanya, E C Ogbodo, C E Onah, A L Asomugha, AK Amah, P C Obi, E I Nwob

Volume :

6

Issue :

4

Abstract :

This is a case-control study designed to assess the glycated haemoglobin, total protein and albumin levels in patients with type 2 diabetes mellitus visiting NAUTH, Nnewi. A total of 114 subjects comprising of 57 diabetic subjects and 57 controls aged between 40 and 73 years were recruited for the study. The patients and controls were aged and sex matched. Subsequently, structured questionnaire were used to obtain patients’ biodata and thereafter, 5mls of blood sample was collected from each patients and 1ml was dispensed into EDTA for the estimation of glycated haemoglobin, and 4ml was dispensed into plain containers for the determination of serum albumin and total protein levels using standard laboratory methods. HbA1c, serum albumin and total protein levels were assayed by using immunoturbidimetric method, Bromo Cresol green Method and Biuret Method respectively. The result revealed that the mean level of HbA1c was significantly higher in the diabetic subjects when compared with the non diabetic subjects (9.621.27 Vs 5.580.62; p= protein did not differ significantly when compared between the diabetic patients and control subjects (p>0.05). This finding implies that there was a poor glycemic control in the diabetic subjects studied. Therefore, there is need for better management of diabetic patients through medication and use of diet and exercise.