Abstract :
Obesity and excess weight are major risk factors for chronic diseases, including type II diabetes, cardiovascular diseases, gastrointestinal disorders and certain forms of cancer.
Understanding the neuroendocrine mechanisms that govern body weight is an important
research priority because such insight could guide the rational design of new agents to
treat obesity. If this becomes a reality, it will be a dream come true for people who are
suffering from obesity. In 2014, 39% of adults aged 18 years and older (38% of men and
40% of women) were overweight. In the modern world, we have a long list of measures
that includes both medical and surgical, which can help us to reduce obesity out of which
the therapeutic vaccines show promise. Recent studies have shown that therapeutic vaccines may be new targets for development of anti-obesity medications. These vaccines
will aim at multiple targets, which include a spectrum of problems ranging from metabolic
derangements to infectious agents including suppressing the appetite-stimulating hormone and blocking absorption of nutrients.
Keyword :
Obesity, Hormonal vaccines, Ghrelin, Flab jab, Adenovirus 36 (Ad36) vaccine.