Abstract :
Acquired perforating collagenosis, is a rare itchy, debilitating cutaneous disorder usually associated with
diabetius mellitius and renal failure or both. The diagnosis is usually based on skin biopsy. The objective
of our study is to review and co-relate the clinical and pathological features in acquired perforating. We
present ten cases of histopathologically proven acquired perforating collagenosis, associated predominantly
with diabetes mellitus. Seven out of ten patients had history of diabetes mellitus for more than ten years.
Thyroid disorders were seen in three patients along with diabetes mellitus. Two had no underlying systemic
diseases. Clinically skin eruptions were multiple, pruritic papules and nodules with central crust formation,
located primarily on lower extremities and occasionally on back.
Keyword :
Acquired perforating dermatosis, Diabetes mellitus, Chronic renal failure.