A study on the morphological spectrum of salivary gland tumors


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Article type :

Original Article

Author :

J Margaret Theresa, A B Harke, Lavanya M

Volume :

7

Issue :

1

Abstract :

Introduction: Salivary gland neoplasm are relatively uncommon and are constitute about 3% of all head and neck neoplasm. Atleast 80% of tumors are located in the parotid gland and the remaining tumors are located in submandibular, sublingual and in minor salivary glands. Objective: The aim is to identify the occurrence of various salivary gland tumors and to categorize them as per WHO classification. Further to identify the histomorphological patterns of salivary gland tumors. Materials and Methods: The biopsy and excised specimens of salivary gland tumors were received in the department of pathology. A gross examination of biopsy and excised specimen was carried out. All the biopsy specimens were well fixed in 10% buffered formalin, processed, embedded with paraffin. After the paraffin blocks were sectioned and stained with Haematoxylin-Eosin, special stains like PAS, Mucicarmin were applied to the sections where ever indicated. The stained slides were examined for histomorphological patterns of salivary gland neoplasms and categorized as per WHO classification. Result and Conclusion: A total of 57 salivary gland tumors specimens were included in the present study. The study report revealed that 40 cases were belong to benign making it 70.2% and the remaining 17 were malignant making it to 29.8% of the total Salivary gland tumors. Pleomorphic Adenoma was the most commonly observed benign tumor. Out of 40 benign tumors 33 were Pleomorphic adenoma (82.5%). Mucoepidermoid carcinoma was the most commonly observed malignant tumor. Out of 17 malignant tumors 6 were Mucoepidermoid carcinomas (35.2%) of all the malignant tumors.

Keyword :

 Salivary gland tumors, Benign tumors, Pleomorphic Adenoma, Malignant tumors, Mucoepidermoid carcinoma.