Abstract :
At present, there are still a lot of diseases pathogenesis not clear, but making use of a new generation of sequencing technology to organisms conduct whole genome sequencing, which for the pathogenesis of many diseases provide a new theoretical basis. So, Which aspects the whole genome sequencing in medical use? In this article, I got through reading the whole genome sequencing of research papers about abroad nearly five years finding that the whole genome sequencing could be widely used in genetic disease, tumor, infectious diseases, infectious epidemic, judge the individual susceptibility to disease, the diagnosis and treatment of a variety of diseases such as biological evolution. This paper reviewed the whole genome sequencing progress in medical application from a genetic disease, tumor, infectious diseases, infectious epidemic, determine the individual susceptibility and biological evolution.
Keyword :
Genome-wide; Whole genome sequencing; Whole genome sequencing applications