Abstract :
This study aimed to improve and assess the transdermal of folic acid through the skin through
non-ionic microemulsions (MEs). Methods and Instruments: Eight MEs were developed with different ratios
of Span 20-to-Tween 80 and folic acid contents. These MEs were characterized for their droplet sizes, rheological
properties. Besides, the encapsulation of folic acid insides the MEs was studied using Fourier-transform infrared
spectroscopy. Furthermore, the flux of formulated folic acid in MEs was evaluated using Franz diffusion cell.
Results: The MEs showed Newtonian viscosity and droplets sizes
Keyword :
Folic acid, transdermal, microemulsions