Abstract :
Human papillomavirus infection is now a well-established cause of many
common cancers like cervical, other anogenital, and head and neck
cancers. The mortality and morbidity rate associated with these cancers
constitute a major burden especially for the underdeveloped and
developing countries of the world, where they are more common.
Traditionally, all these subsites are being treated with different
chemoradiation protocols with variable results. Toxicities associated
with the standard high dose chemoradiation protocols form a major
obstacle in the completion of treatment for these patients and often affects
the outcome negatively. Personal experience and published reports and
reviews suggests that HPV associated squamous cell cancers are a
distinct biological sub group of cancer which can be treated safely with
reduced intensity of chemoradiation. The establishment of a similar de-intensified chemoradiation protocol for all
HPVassociated squamous cell carcinoma will certainly improve the quality of life of such patients.
Keyword :
T. cordifolia, Natural Antioxidants, Post heparin lipolytic activity, Streptozotocin induced diabetes, plant antioxidant.