Abstract :
Introduction: Acute lung injury (ALI) remains a significant source of morbidity and mortality in the critically ill patient population. Defined by a constellation of clinical criteria (acute onset of bilateral pulmonary infiltrates with hypoxemia without evidence of hydrostatic pulmonary edema). Pathogenesis of ALI is explained by injury to both the vascular endothelium and alveolar epithelium.
Materials and Methods : This was a prospective, observational and cross-sectional study conducted in the medical ICU of Department of Pulmonology at tertiary care teaching hospital between May 2018 and April 2019. Patients with ALI/ARDS were identified through a prospective daily ICU surveillance, based on the American-European Consensus Conference criteria (AECC).
Result : In our study, we had a total of 59 patient, out of which 43 survived. We had a mortally rate of 27.2%. Most of the patients were 25-60 years i.e., 23 out of 43, followed by Conclusions: Pneumonia and tropical diseases are the common risk factor for the ARDS/ALI. The presence of co-morbid conditions also affects the outcome of ALI/ARDS patients. MODS of >4, LIs >2 and APACHE II >2 had associated with higher mortality.
Keyword :
Acute respiratory distress syndrome (ARDS), Pulmonary edema, Acute respiratory failure.