Abstract :
Introduction: Wound infection is a common problem in obstetric and surgical procedures. It is not clear
whether perioperative prophylaxis of one portion of anti-infective agents is sufficient to prevent wound
contamination. This test was aimed at assessing whether anti-infection of one perioperative part was
successful in counteracting diseases after use in women undergoing caesarean section.
Materials and Methods: This is a multicentre study. Participants were given a single dose of 1 g of
cefotaxime intravenously before surgery, and the incidence of postoperative complications such as wound
infections, wound resuturing, etc. was monitored.
Results: The study included 100 elective caesarean sections. Cefotaxime injection of 1 g IV was injected
30 minutes before surgery. The incidence of febrile morbidity was seen in 10 %, and wound infection was
in 5% of total patient. The microorganisms isolated from the wound infection were E. coli, Pseudomonas,
which were sensitive to cefoperazone-sulbactum and linezolid. The average length of hospital stay was 4
days.
Conclusion: A single prophylactic dose of cefotaxime is effective for the prevention of postoperative
infection. The results obtained in this study shows that single-dose antibiotic prophylaxis is effective.
The resistance of microorganisms can be prevented with this prophylactic single-dose antibiotic. This
prospective study confirms that one-time antibiotic prophylaxis had a positive effect on women undergoing
a planned caesarean section.
Keyword :
Elective cesarean section, Single dose of antibiotic, Prevention, Wound infection.