Volume :
5
Issue :
2
Abstract :
Background Thyroid hormones have significant effects on lipid metabolism and homocysteine levels. Decrease in thyroid hormone levels may alter the homeostasis of lipid metabolism and homocysteine levels. Objectives To study the incidence of hyperhomocysteinemia and hypercholesterolemia in patients with hypothyroidism, and to find out the correlation of homocysteine with cholesterol levels, thyroid hormones and thyroid-stimulating hormone (TSH) in newly detected hypothyroid patients. Methods In this prospective case-control study, 30 hypothyroid patients (case group) and 30 euthyroid controls were included. Patients with a TSH level >4.78 mIU/mL were considered in the case group and those with TSH level