The association of Hypothyroidism medications and Systemic Lupus Erythematosus SLE: A case study of drug induced Lupus


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Introduction Hypothyroidism is a condition which requires iodine levels to be augmented and adjusted for the proper function of thyroid gland. Hypothyroidism refers to any state in which thyroid hormone production is below normal. The thyroid gland is regulated by, the pituitary gland. There is a risk that the medicines given to treat hypothyroidism can cause systemic lupus erythmatosus SLE. It is an autoimmune disease in which the bodys immune system mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain. SLE is much more common in women than men. Case presentation A 45 year old female patient visited the hospital with complaints of itching on the right leg. There were symptoms risking the presence of SLE which later, the patient was then diagnosed with the disease. Upon investigation it was suspected a case of drug induced lupus as the patient had hypothyroidism two years ago and was on levothyroxine therapy. Conclusion This report presents a case with an association between hypothyroidism medications and SLE. Risk of morbidity can be controlled by maintaining proper iodine level as well as to reduce the symptoms of SLE. The presence of either condition was associated with a higher frequency of both anti-microsomal and anti-thyroglobulin antibodies.
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