Abstract :
Background and Objective: Pulsed electromagnetic fields (PEMFs) in low frequencies and intensities have been
reportedly effective in osteoporosis treatment and prevention. Preclinical and clinical studies have shown PEMFs
alter the osteoblast and osteoclast processes, enhance bone mineral density (BMD), and reduce bony pain in
osteoporosis patients. The well-design studies in this field are in early stages and no definitive dose-response has been
determined. The present study aims to comprehensively review the therapeutic efficacies of PEMFs in osteoporosis
treatment and prevention
Methods: The databases of Web of Sciences (1970-2017), PubMed (1980-2017), Embase (1980-2017), Google
Scholar (1980-2017) and additional resources were searched using the key words "pulsed electromagnetic fields" OR
"electromagnetic fields" AND "osteoporosis". The abstracts of the retrieved records to select the relevant records for
full review. Considering the variances in the study design and stimulation parameters we conduct a comprehensive
review aiming the therapeutic efficacies oo PEMFs in osteoporosis treatment and physiological effects.
Results: Current evidence on the efficacy of PEMFs in osteoporosis is moderate and further studies need to be
conducted. The PEMFs have preventive and therapeutic effects on osteoporosis. To yield the therapeutic effects,
relatively long treatment period ranging two to three month of daily 30-40 min stimulations are required. The main
effects of PEMFs for osteoporosis treatment are reducing chronic bony pain, increasing BMD and osteoblast, bone
strength and enhancing bone metabolism.
Conclusion: Low-frequency PEMFs relieves the pain of primary osteoporosis quickly and efficiently, enhances bone
formation and increases BMD of secondary osteoporosis. But the effects of PEMFs on bone mineral density of
primary osteoporosis and bone.
Keyword :
Electromagnetic fields, Osteoporosis, Treatment, Prevention