Abstract :
Nicotine acts on nearly every Physiological System of the human body. The effects of
nicotine on the Peripheral nervous system have been extensively studied and are now quite
well understood. The effects of nicotine on the central nervous system are more complex
and our understanding of these effects is limited. The Pharmacokinetic and
Pharmacodynamics of nicotine with an emphasis on the Psychopharmacological basis of
nicotine dependence. In South America, seeking for psychoactive effects of nicotine might
be as old as the origin of horticulture, beginning some eight thousand years ago present
Ritual tobacco was used in shamanism aimed to achieve acute nicotine intoxication, which
induced in the shamans’ catatonic states representing symbolic death. The effect of large
doses of nicotine on the autonomic and central nervous system gave the impression of a
gradual death of the shaman, who then returned miraculously to life (Wilbert 1987).
Regular, moderate use of nicotine alone or in combination is a well-known, widely
established and loved practice of men and women both. Despite, health consequences to
these pharmacological agents, people continue, quite persistently, to consume these
substances and afford much value to the pleasure of a regular intake.
Keyword :
Addiction, Psychoactive substances, Respiratory, Nicotine