Synthesis and Anti tubercular activity of some new N’-(3-hydroxy-3, 4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid derivatives


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Article type :

Original Article

Author :

Shripad Potadar, Ramaling Kotnal

Volume :

7

Issue :

2

Abstract :

A new series new N’-(3-hydroxy-3,4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid derivatives were designed and synthesized. The newly synthesized compounds were evaluated for their anti-tb activity. The structure of the synthesized compounds was confirmed by elemental analysis and spectral data (IR, 1H NMR and Mass). The data obtained from biological screening revealed that; synthesized compounds showed the good to moderate anti-tb activities.

Keyword :

 Quinoxaline, Orthophenylenediamine, Alloxane and antimycobacterial.