Study of transfusion transmissible infections in donors in a tertiary care hospital in North Karnataka region


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Article type :

Original Article

Author :

S. B Shivashetty, Md. Hamed Altaf Mali

Volume :

4

Issue :

4

Abstract :

Introduction: Blood safety comprises provisions of safe, adequate and quality blood and its components to the needy patients. Blood transfusion is a double edge sword which involves life saving of patients and also subjected to risk of transfusion transmissible infections such as HIV, HBV, HCV, syphilis etc. This risk has been reduced dramatically by routine screening of blood donors . Objective: To study the serological prevalence of transfusion transmissible infections among donors and to find any correlation between these infections and blood groups. Materials and Methods : This study was conducted for a period of three years (JAN 2016- DEC2018), carried out in blood bank of Basaveshwara Teaching and General Hospital, Kalaburagi in North Karnataka. A total of 13249 donors were analysed for transfusion transmitted infections. Results: Total of 13249 donors were screened during the study period and 253 donors were found seropositive for transfusion transmissible infections (1.88%). In which, maximum 237 donors were positive for HBV (1.78%), followed by 12 with HIV(0.090%), 3 with malaria (0.022%) and 1 with HCV (0.0079%) respectively. Seropositive for HBV was more common in B blood group donors, while HIV was maximum in A blood group donors and only 1 case of HCV was seen in AB blood group. Conclusion: The results of this study are comparable to various other studies done in India. There was no significant association between various blood group antigens and 2 transfusion transmissible infections. Voluntary donations are safer as compared to replacement ones and should be encouraged. Efforts should me made to increase the awareness regarding voluntary blood donation in the local population.

Keyword :

 Blood donors, Transfusion transmissible infections, Seropositivity.