Study of the Association between Serum Vitamin D 25(OH) D levels, Muscle Strength and fall among Elderly


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Volume :

3

Issue :

2

Abstract :

Background: Reduced Vitamin D levels are common in elders. Deficiency predominantly affects the proximal muscles and contributes to falls increasing the risk of fractures among elders. Objective: To study the association between serum Vitamin D 25(OH) D levels, muscle strength and falls among elderly. Methods: 204 individuals aged more than 60 were included. It was a prospective Cross Sectional study. Historical data included motor weakness, of both proximal and distal muscles, falls &co morbidities. CGA including ADL was done. Motor power was tested using MRC grading. Vitamin D 25 (OH) levels was estimated using CLIA method. Results: There were 119 female and 85 male subjects. 86(42.2%), 99(48.5%) of them had severe deficiency (< 10 ng/ml) & insufficiency (10-25ng/ml) respectively. Only 19 (9.3%) had normal Vitamin D levels. 111(54.4%) individuals had proximal lower limb motor weakness (Symptomatic plus MRC grading). 86 (77.5%) among these had severe Vitamin D deficiency (p< 0.001). 77 (37.7%) had proximal upper limb motor weakness. 64 (83%) among them had severe Vitamin D deficiency (p< 0.001) .Strikingly it was found that severe Vitamin D deficiency was also associated with distal muscle weakness. 36 (17.6%) had falls. 35 among them (97.2%) had severe Vitamin D deficiency (p

Keyword :

ADL, Falls, muscle weakness, Vitamin D.
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